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Monica Kariuki is about ready to give up on farming. What is driving her off her 10 acres of land outside Nairobi isn’t bad weather, pests or blight – the traditional agricultural curses – but fertilizer: It costs too much.

Despite thousands of miles separating her from the battlefields of Ukraine, Kariuki and her cabbage, corn and spinach farm are indirect victims of Russian President Vladimir Putin’s invasion. The war has pushed up the price of natural gas, a key ingredient in fertilizer, and has led to severe sanctions against Russia, a major exporter of fertilizer.

Kariuki used to spend 20,000 Kenyan shillings, or about $175, to fertilize her entire farm. Now, she would need to spend five times as much. Continuing to work the land, she said, would yield nothing but losses.

“I cannot continue with the farming business. I am quitting farming to try something else,’’ she said.

Higher fertilizer prices are making the world’s food supply more expensive and less abundant, as farmers skimp on nutrients for their crops and get lower yields. While the ripples will be felt by grocery shoppers in wealthy countries, the squeeze on food supplies will land hardest on families in poorer countries. It could hardly come at a worse time: The U.N. Food and Agriculture Organization said last week that its world food-price index in March reached the highest level since it started in 1990.

The fertilizer crunch threatens to further limit worldwide food supplies, already constrained by the disruption of crucial grain shipments from Ukraine and Russia. The loss of those affordable supplies of wheat, barley and other grains raises the prospect of food shortages and political instability in Middle Eastern, African and some Asian countries where millions rely on subsidized bread and cheap noodles.

“Food prices will skyrocket because farmers will have to make profit, so what happens to consumers?’’ said Uche Anyanwu, an agricultural expert at the University of Nigeria.

The aid group Action Aid warns that families in the Horn of Africa are already being driven “to the brink of survival.’’

The U.N. says Russia is the world’s No. 1 exporter of nitrogen fertilizer and No. 2 in phosphorus and potassium fertilizers. Its ally Belarus, also contending with Western sanctions, is another major fertilizer producer.

Many developing countries – including Mongolia, Honduras, Cameroon, Ghana, Senegal, Mexico and Guatemala – rely on Russia for at least a fifth of their imports.

The conflict also has driven up the already-exorbitant price of natural gas, used to make nitrogen fertilizer. The result: European energy prices so high that some fertilizer companies “have closed their businesses and stopped operating their plants,’’ said David Laborde, a researcher at the International Food Policy Research Institute.

For corn and cabbage farmer Jackson Koeth, 55, of Eldoret in western Kenya, the conflict in Ukraine was distant and puzzling until he had to decide whether to go ahead with the planting season. Fertilizer prices had doubled from last year.

Koeth said he decided to keep planting but only on half the acreage of years past. Yet he doubts he can make a profit with fertilizer so costly.

Greek farmer Dimitris Filis, who grows olives, oranges and lemons, said “you have to search to find’’ ammonia nitrate and that the cost of fertilizing a 10-hectare (25-acre) olive grove has doubled to 560 euros ($310). While selling his wares at an Athens farm market, he said most farmers plan to skip fertilizing their olive and orange groves this year.

“Many people will not use fertilizers at all, and this as a result, lowers the quality of the production and the production itself, and slowly, slowly at one point, they won’t be able to farm their land because there will be no income,’’ Filis said.

In China, the price of potash – potassium-rich salt used as fertilizer – is up 86% from a year earlier. Nitrogen fertilizer prices have climbed 39% and phosphorus fertilizer is up 10%.

In the eastern Chinese city of Tai’an, the manager of a 35-family cooperative that raises wheat and corn said fertilizer prices have jumped 40% since the start of the year.

“We can hardly make any money,” said the manager, who would give only his surname, Zhao.

Terry Farms, which grows produce on 2,100 acres largely in Ventura, California, has seen prices of some fertilizer formulations double; others are up 20%. Shifting fertilizers is risky, vice president William Terry said, because cheaper versions might not give “the crop what it needs as a food source.”

As the growing season approaches in Maine, potato farmers are grappling with a 70% to 100% increase in fertilizer prices from last year, depending on the blend.

“I think it’s going to be a pretty expensive crop, no matter what you’re putting in the ground, from fertilizer to fuel, labor, electrical and everything else,” said Donald Flannery, executive director of the Maine Potato Board.

In Prudentopolis, a town in Brazil’s Parana state, farmer Edimilson Rickli showed off a warehouse that would normally be packed with fertilizer bags but has only enough to last a few more weeks. He’s worried that, with the war in Ukraine showing no sign of letting up, he’ll have to go without fertilizer when he plants wheat, barley and oats next month.

“The question is: Where Brazil is going to buy more fertilizer from?” he said. “We have to find other markets.”

Other countries are hoping to help fill the gaps. Nigeria, for example, opened Africa’s largest fertilizer factory last month, and the $2.5 billion plant has already shipped fertilizer to the United States, Brazil, India and Mexico.

India, meanwhile, is seeking more fertilizer imports from Israel, Oman, Canada and Saudi Arabia to make up for lost shipments from Russia and Belarus.

“If the supply shortage gets worse, we will produce less,” said Kishor Rungta of the nonprofit Fertiliser Association of India. “That’s why we need to look for options to get more fertilizers in the country.”

Agricultural firms are providing support for farmers, especially in Africa where poverty often limits access to vital farm inputs. In Kenya, Apollo Agriculture is helping farmers get fertilizer and access to finance.

“Some farmers are skipping the planting season and others are going into some other ventures such as buying goats to cope,” said Benjamin Njenga, co-founder of the firm. “So these support services go a long way for them.”

Governments are helping, too. The U.S. Department of Agriculture announced last month that it was issuing $250 million in grants to support U.S. fertilizer production. The Swiss government has released part of its nitrogen fertilizer reserves.

Still, there’s no easy answer to the double whammy of higher fertilizer prices and limited supplies. The next 12 to 18 months, food researcher LaBorde said, “will be difficult.”

The market already was “super, super tight” before the war, said Kathy Mathers of the Fertilizer Institute trade group.

“Unfortunately, in many cases, growers are just happy to get fertilizer at all,’’ she said.